305 miles down I-5 SOUTH.
304.56 miles (490.14 kilometres)
According to Goole Earth, it is 450 miles from Seattle,Wa. to Medford,Or. or 7hrs. & 8 mins. driving time and distance. Brewski
175 miles taking this route: Take OR-140 WEST from Lakeview to OR-62. Turn left onto OR-62 towards MEDFORD. Take OR-62 SOUTH to Medford. OR-62 is Crater Lake Hwy in Medford.
221.42 miles (356.34 kilometres)