How many protons can be lost by malonic acid?

Answer:

Malonic acid has pKa values of 2.83 (pK1) and 5.69 (pK2).

If malonic esters are used then on treatment with a strong base like sodium ethoxide, the methylene (-CH2-) hydrogen can be deprotonated, but I am not sure if that is possible for malonic acid as that will lead to a tri-anion.

First answer by Rnp 279. Last edit by Rnp 279. Contributor trust: 310 [recommend contributor recommended]. Question popularity: 34 [recommend question].