In most cases, this depends on the tolerance levels of the patient both physically and emotionally. Each course of chemotherapy weakens the immune system and general energy reserve for each organ and system affected. That is why repeated courses of therapy are usually cycled with off-periods of weeks to months, to allow recuperation of the patient without significant re-growth of the cancer (hopefully). The only exception are the "red meds," like doxorubicin or daunorubicin. these tend to have lifetime limits of 400mg per patient due to the cumulative cardiac toxicity on the heart.
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