In the U.S., either 2,088 hours or 1,928 hours is often used as a standard work year for HR purposes. The latter figure accounts for 20 work days of annual leave.
Full year (no leave)
Work hours -- 2,088
Work week -- 52.2
Work days -- 261
Full year (with 4 week leave)
Work hours -- 1,928
Work week -- 48.2
Work days -- 241