When taken orally benzodiazepines are not respiratory depressants (they don't slow the breathing as opiates do)* and so it would be difficult to cause death by over-dose with them.
In rats 4000 mg per kg of body weight kills about half the time. So assuming humans are the same, which is not a safe assumption, an average size person would need to take about 280,000 mg to have a 50-50 chance of death.
* There have been some studies showing slight, probably clinically insignificant, respiratory depression with large doses of fast acting benzos given IV.
Most benzodiazepines have a high LD50 (the amount needed to kill 50% of test subjects.) The LD50 is not a perfect way of determining the letal amount but it shouls provide a ball park. For rats the LD50 of clonazepam is 4000mg per kg and for rabbits it is 2000mg per kilogram. If the average human weighed 70kg (around 160lb) then based on the LD50 for rabbits 140,000mg would be needed to kill a person.
Clonazepam tablets are available in 0.5mg, 1mg and 2mg. 280,000 0.5mg, 140,000 1mg or 70,000 2mg tablets would be needed to kill.
Most benzodiazepines have a high LD50 (the amount needed to kill 50% of test subjects.) The LD50 is not a perfect way of determining the letal amount but it shouls provide a ball park. For rats the LD50 of clonazepam is 4000mg per kg and for rabbits it is 2000mg per kilogram. If the average human weighed 70kg (around 160lb) then based on the LD50 for rabbits, 140,000mg would be needed to kill a person.
Clonazepam tablets are available in 0.5mg, 1mg and 2mg. 280,000 0.5mg, 140,000 1mg or 70,000 2mg tablets would be needed to kill.
What if U combine it with methadone maintenance at 200 mgs a day
over one hundred
Apparently more than10
30
Clonazepam is not an opiate, so you can take it even if you're already on Suboxone. A few years ago I was prescribed clonazepam, on top of my regular dose of Suboxone. Just don't take more than a normal dose of either drug: as they are both depressants, there is a risk of overdose if you take too much.
By taking more than was prescribed for you. This was no the question asked! Pay attention! DO YOU HAVE ADD?
Yes you can take the 2, but be careful about how much of each you take.
0.6
Clonazepam (Klonipin), like most benzodiazepams, is not very lethal at all. While human LD50's are indeterminate, the rat LD50 is around 4000mg/kg. Extrapolating that up for humans indicates a huge amount. The initial dosage of clonazepam is around 1.5mg TID (three times a day), so anything over this is technically an overdose, although it most likely will just make you sleepy. But the amount required for an acute, lethal overdose is undetermined.
It is unlikely that you would be able to kill yourself with Klonopin (clonazepam). The amount that it would take to cause severe impairment depends on the person.
The safest dose of Clonazepam is 20mg daily. Anything more than this in one (1) twenty four (24) hour period is considered an overdose.
If you take 8 20mg at once will u overdose.
one pound
Yes, a dog can overdose on Benadryl, and it doesn't take as much as you might think.
u take to much drugs or do to much drugs
Yes, one can overdose on clonazepam (Klonopin). Clonazepam is a benzodiazepine medication, also called a sedative-hypnotic, used most commonly in the treatment of anxiety disorders. Overdose causes symptoms of drowsiness, alterations in mental status, confusion, excessive somnolence, and coma. In some circumstances (and usually when mixed with other sedating medications or drugs, such as opioids or alcohol) overdose can lead to respiratory arrest and death.