15-20 mg will get you pretty high your first time. Anything more than that I would use Cold Water Extraction because the acetaminophen can really hurt your liver.
You need to discuss this with your doctor - Vicodin contains acetaminophen (Tylenol) taking more than 1000mg/dose or 4000mg per day can cause liver toxicity.Vicodin 5/500 - taking 2 tablets equals...
It all depends on your body weight and tolerance. If you've never taken Vicodin before, 5mg orally (taking the pill whole) would probably produce a slight buzz/dizziness. Crushing and snorting the...