The series began in 2000, when Frankie Muniz (the actor playing Malcolm) was fifteen.
About 10...thousand. Years old...
The show is 20 years old.
Twenty-five (25) years old is the age of U.S. actor, producer and writer Justin Tyler Berfield (b. February 25, 1986), who played Reese in "Malcolm in the Middle."
Reese from malcolm in the middle is 25.(In 2011)