Answer:
When King Ferdinand and Queen Isabella conquered all of Spain from the Muslims, they made all Muslims and Jews convert to Christianity. Before that, Muslims went to Mecca at least once in their life and frequently many times. While those trips served a religious purpose, they also served a commercial purpose. Muslims from Spain to China formed commercial partnerships. Forced conversion of Muslims ended that trade.The law likewise brought forced conversion of Jews. The law prohibited the Jews from owning property. As a result, they developed the sciences, medicine, and banking. They made Spain one of the richest and most advanced nations on the face of the earth. Copernicus and Galileo translated works by Spanish Jews. While the Muslims had their trade routes through the Mediterranean and through Africa, the Jews had contacts throughout Europe. The forced conversions ended those contacts.