What would you like to do?

If you wanted to block cAMP signaling by targeting PKA what might you do that would block PKA activity?

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What is is pKa?

pKa is the acid dissociation constant for any acid. It is a measure of strength of the acid.

PKa of NaHCO3?

The pKa value for sodium bicarbonate (NaHCO3) is 10.3. This provides a measure of the acid strength of bicarbonate. People often make the mistake of reporting the pKa value

What is the pka of cyclizine?

pKa1 = 2.16 pKa2 = 8.05 Ref: Newton, D.W., Murray, w.j., Lovell, M.W. pKa Determination of benzhydrylpiperazine antihistamines in aqueous and aqueous methanol solutions (1982)