If you wanted to block cAMP signaling by targeting PKA what might you do that would block PKA activity?

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What is is pKa?

pKa is the acid dissociation constant for any acid. It is a measure of strength of the acid.

PKa of NaHCO3?

The pKa value for sodium bicarbonate (NaHCO3) is 10.3. This provides a measure of the acid strength of bicarbonate. People often make the mistake of reporting the pKa value

What is the pka of cyclizine?

pKa1 = 2.16 pKa2 = 8.05 Ref: Newton, D.W., Murray, w.j., Lovell, M.W. pKa Determination of benzhydrylpiperazine antihistamines in aqueous and aqueous methanol solutions (1982

What is the pKa of Hexane?

pKa is measured for acid in aqueous solution while hexane is an organic liquid immiscible with water so pKa value is meaning less for hexane.