Cholinesterase inhibitors are drugs that block the activity of an enzyme in the brain called cholinesterase. Cholinesterase breaks apart the neurotransmitter acetylcholine, which is vital for the...
The need for the drug varies from day to day and during the same day in response to infection, menstruation, emotional stress, and hot weather. Different muscles respond differently.
Essentially a lot of the pathways affected in AD are run by AceylCholine so a central ACHE inhibitor would allow increased ACH in the CNS and bypass the damage that may be inhibiting the synaptic...