I have a few friends who went from homeschooling to public school, and they seemed to have no problem. I would just suggest not to be too shy, and just try to converse a little.
In many cases there is a transition period, but once you get through that and make a few friends with your peers you should do just fine. If you were home-schooled and your parents made sure you had time to be around your peers you should fit in quite nicely. Take it slow and easy and don't be afraid because you won't be in school forever and most kids are just plain shy.