Answer:
Yes, the Trail of Tears is a very famous Trail. Anyone in Grades 5-8 learns about it.
Here is the definition I found in the Text book:
Trail of Tears (1838-39) an 800 mile forced march made by the Cherokee from their homeland in Georgia to Indian Territory; resulted in the deathsof almost 1/4 of the Cherokee population.
So, yes. It's famous alright... :D