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neurotransmitter (:
The chemical most commonly found in both pre- and postganglionic synapses in the parasympathetic system is the neurotransmitter acetylcholine.
There are several types of synapses in the body. The most commonly discussed type is the chemical synapse, but other types of synapses include electrical synapses and immunological synapses. Because chemical synapses are the most commonly discussed synapses in general, that's probably what this question is referring to.A chemical synapse is a small gap, or commonly referred to as a connection, between two cells that allows for the first cell (the presynaptic cell) to communicate with the second cell (the postsynaptic cell) through a chemical signal. These chemical signals are called neurotransmitters, and once they are released by the presynaptic cell, they act on the postsynaptic cell through specialized protein molecules called neurotransmitter receptors.The actions triggered by a neurotransmitter binding its receptor on the postsynaptic cell are highly varied. They vary according to the type, quantity, and frequency of neurotransmitter release, the specific receptor involved, the type of cell that is receiving the neurotransmitter signal, among other things. For example, a neurotransmitter called glutamate typically causes activation of the postsynaptic cell, while a neurotransmitter called GABA typically inhibits postsynaptic cells. Likewise, if the postsynaptic cell belongs to a gland, then activity in that cell may promote secretion, while inhibition may hinder secretion. If the postsynaptic cell is a muscle fiber, then activation triggers muscle contraction, while inhibition causes relaxation.A synapse is a connection which allows for the transmission of nerve impulses. Synapses can be found at the points where nerve cells meet other nerve cells, and where nerve cells interface with glandular and muscular cells. In all cases, this connection allows for the one-way movement of data. The human body contains trillions of synapses, and at any given time, huge numbers of these connections are active.
acetylcholine (ACh)
they stop the releasing of a chemical in synapses called neurotransmitter, stopping the pain travelling through the nervous system.
The word synaptic is an adjective which means, pertaining to the synapses. So, I could describe dopamine as a chemical that has a synaptic function, as a neurotransmitter.
Chemical synapses are specialized junctions through which neurons signal to each other and to non-neuronal cells such as those in muscles or glands. At a chemical synapse, one neuron releases a neurotransmitter into a small space (the synapse) that is adjacent to another neuron.
There are several types of synapses in the body. The most commonly discussed type is the chemical synapse, but other types of synapses include electrical synapses and immunological synapses. Because chemical synapses are the most commonly discussed synapses in general, that's probably what this question is referring to.A chemical synapse is a small gap, or commonly referred to as a connection, between two cells that allows for the first cell (the presynaptic cell) to communicate with the second cell (the postsynaptic cell) through a chemical signal. These chemical signals are called neurotransmitters, and once they are released by the presynaptic cell, they act on the postsynaptic cell through specialized protein molecules called neurotransmitter receptors.The actions triggered by a neurotransmitter binding its receptor on the postsynaptic cell are highly varied. They vary according to the type, quantity, and frequency of neurotransmitter release, the specific receptor involved, the type of cell that is receiving the neurotransmitter signal, among other things. For example, a neurotransmitter called glutamate typically causes activation of the postsynaptic cell, while a neurotransmitter called GABA typically inhibits postsynaptic cells. Likewise, if the postsynaptic cell belongs to a gland, then activity in that cell may promote secretion, while inhibition may hinder secretion. If the postsynaptic cell is a muscle fiber, then activation triggers muscle contraction, while inhibition causes relaxation.A synapse is a connection which allows for the transmission of nerve impulses. Synapses can be found at the points where nerve cells meet other nerve cells, and where nerve cells interface with glandular and muscular cells. In all cases, this connection allows for the one-way movement of data. The human body contains trillions of synapses, and at any given time, huge numbers of these connections are active.
There is not just one chemical secreted into synapses (the gaps between neurons); instead, there are many chemicals secreted from the terminal buttons of neurons into the synapses. They are called "neurotransmitters."
There are many kinds of synapses in the nervous system, but I assume you're talking about the most commonly discussed type: the chemical synapse. These synapses join nerve cells (called neurons) and allow them to communicate.Communication across a chemical synapse is called synaptic transmission. It occurs when electrical activity (called an action potential) in the first cell triggers the release of a chemical signal (called a neurotransmitter) across the synapse. The neurotransmitter travels across the synapse by a process of diffusion, ultimately reaching its target, the second cell. There, the neurotransmitter binds a special type of protein molecule called a neurotransmitter receptor, which changes its shape in response to binding the neurotransmitter. This shape change results in a series of subsequent changes in the second cell. These subsequent changes result in alterations in the electrical activity of the second cell.The gist of synaptic transmission is that it allows the electrical activity in one nerve cell to influence the electrical activity of another.
The action potential reaches the pre synaptic area, which opens a voltage sensitive Calcium ion gate, allowing calcium ions to move in via diffusion along an electrochemical gradient. The period of refraction (repolarisation) closes this gate. The increased conc. of Calcium ions pushes vesicles with neurotransmitter to the presynaptic membrane, where they fuse and exocytosis causes the neurotransmitter to be released across the synaptic cleft. The NT binds to a receptor which opens Na+ channels on the postsynaptic membrane, allowing depolarisation due to Na+ diffusion which continues the action potential across the other neurone. The neurotransmitters are broken down by enzymes or are reabsorbed by endocytosis into the presynaptic cleft, using energy from ATP.
You are likely referring to receptor proteins. Receptor proteins are used extensively in the endocrine, nervous and immune systems to carry out signal transduction and communication between cells. For example, an endocrine receptor may be the insulin receptor, which dimerizes upon signal molecule (insulin) binding and induces a series of changes in the cell leading to increased glucose uptake, increased glycolysis and decreased gluconeogenesis. A nervous system receptor may be a neurotransmitter receptor located at synapses that induces an action potential in the downstream neuron if it binds to a neurotransmitter released by the upstream neuron. The immune system makes extensive use of receptors and these receptors may be cell-surface bound or even soluble (e.g. antibodies). They are involved either in recognizing foreign molecules, transmission of activation signals for leukocytes, or administration of death (apoptosis) signals to other kinds of cells.