Is there a cure for Celiac Disease?

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No, there is no known cure for Celiac Disease. There are however ongoing studies for different therapies. Some show some real promise but this may be three, five or ten years down the road. The ONLY treatment for this disease is to go on a strict Gluten Free diet. That means no wheat, barley, Rye or Oats (Oats are safe but only from a certified Gluten free mfger and only after having been on a gluten free diet for six months).

There is no cheating once on the diet.. to cheat even once a month would seriously setback ones healing of the small intestine.

Current research:

www.nexpep.com is supposed to start clinical trials of its vaccine therapy 2008.

www.albatherapeutics.com is almost into phase III of AT-1001, which will enable Celiacs to eat out w/o fear of cross contamination, but won't let you eat gluten like a slice of pizza. Studies are showing better results than anticipated and who knows, maybe it will allow someone to have a cheat day now an then? The premise is that Celiacs have leaky guts, by closing the leak the gluten peptide is unable to cause an autoimmune response which causes the damage to the small intestine.

http://www.alvinepharma.com/ is starting phase I this year on its EP-B2, which is a peptide prolease that is supposed to rapidly consume gluten peptide and like "pac man" break its acid chain down small enough that the body no longer recognizes the gluten as an enemy. Studies so far indicate that it too will only limit cross contamination issues, but it may do more? Testing will take at least five years.

Finally...

There is other enzyme therapies being explored in Europe, particularly Holland. This holds greater promise as the enzyme is supposed to like hostile acid environments, its already being mfg'd for industrial uses so its cheap to produce. This enzyme is so strong that the early reports are that no gluten remains after taking the treatment. So far its been tested in a lab and on some dogs... again, it will take years for anyone to get this fully tested.

There you have it.. other than research to show what else this horrible disease causes there seems to be little other interest by the medical community on a whole... no money in cures only in pills...

First answer by ID1247680995. Last edit by ID1247680995. Question popularity: 1 [recommend question]