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i believe that the strongest non-quest enemy is Umbra
the mustain
A chicken THE STRONGEST ENEMY IN THE SERIES!
Omega Shenron.
Emerald Weapon
Ancient dragon
enemies
Meaning, you kill the weaker enemy to scare the stronger enemy.
You just have to be stronger than the enemy.
krangs 120 ft. robot
In the Comics I would say it is Venom, but I don't know who it would be in videogames...
"Arch Enemy" by Frank Beddor has 434 pages in the hardcover version.