It takes about 8 hours of driving time (depending on traffic, of course) to go from San Diego to San Francisco on I-5.
Depending traffic it takes about 8 hours to drive from San Francisco to San Diego traveling south on I-5.It takes approximately 8 hours to drive from San Francisco to San Diego on I-5 (the quickest...
About 500 miles.
737.8 kilometres (458.45 miles)
It is 502 miles from San Francisco to San Diego.