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You will probably always be sensitive to opiates because that's the way your brain has been conditioned. Like any addiction, to opiates or alcohol or nicotine, the brain's neural receptors will always be ready to want and accept the particular substance they've been "trained" to need. Opiate blockers, like Anabuse for alcohol, doesn't alter your brain's and body's physiological reactions to the substance, they are just artificial deterrents that have no effect on behavior or the treatment of the underlying causes of opiate/alcohol dependence.

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16y ago
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13y ago

It depends on how much of the blocker you're taking, how much you weigh, and your new tolerance to narcotics since last taking them. First of all, the opiate blocker has to be completely out of your system for you to feel the full effects. I am presently taking methadone to treat my addiction to heroin, and i have recently tried (twice) to get high from heroin. I tried both sniffing and shooting it, and nothing happened at all. I have to warn those who are going to get high after being sober for a certain amount of time! I have had many friends over dose and die their first time getting high again after being sober. REMEMBER your tolerance IS NOT what it used to be when you were regularly getting high!! it will take alot LESS to feel the effects of whatever drug you are going to do..so be careful and take it slow. although your better off staying on the right path and not getting high at all...all of your efforts to get clean will just go to waste. take the advice from someone who is going through the same thing you are. Ive slipped up and its not worth it..save your money and your life.

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Q: How long after taking an opiate blocker before you can get high again?
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