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Presynaptic neurons release neurotransmitters by?

Answer:
An action potential travels down the neuron and reaches the presynaptic knob.
This causes the Calcium ion channels to open and allow an influx of calcium into the knob.
The increased concentration of calcium causes the secretory vesicles within the knob to bind to the outer membrane and release their neurotransmitter (e.g. ACh) into the synaptic cleft.
First answer by Frannymilewizc. Last edit by Frannymilewizc. Contributor trust: 2 [recommend contributor recommended]. Question popularity: 0 [recommend question].

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