Agranulocytosis has been associated with clozapine. This is a potentially fatal reaction, but can be prevented with careful monitoring of the white blood count.
It is most commonly associated with haloperidol, long-acting fluphenazine, but has occurred with thiothixene, thioridazine, and clozapine, and may occur with other agents.
Anticholinergic effects, particularly dry mouth, have been reported with all of the phenothiazines, and can be severe enough to cause patients to discontinue their medication.
sulfonylureas have a particularly long list of drug interactions.actions of oral hypoglycemic agents may be strengthened by highly protein bound drugs,including...