Astringents (drying agents), such as witch hazel, calamine, and zinc oxide. These help shrink hemorrhoids by pulling water out of the swollen tissue. This, in turn, helps relieve itching, burning, and irritation.
epinephrine base, epinephrine hydrochloride, ephedrine sulfate and phenylephrine hydrochloride that reduce swelling and relieve itching and discomfort by tightening blood vessels
cocoa butter, lanolin, glycerin, mineral oil, and shark liver oil which soothe irritated tissues and form a protective barrier to prevent further irritation.