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Barbiturates are drugs that act as central nervous system depressants, and can therefore produce a wide spectrum of effects, from mild sedation to total anesthesia. They are also effective as anxiolytics, hypnotics, and anticonvulsants.

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7y ago
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15y ago

Barbiturates are depressants that act on the CNS. Barbituates and are still widely used as surgical anesthetics. The most common recreational barbituate would have to be doctor-prescribed sleeping pills and sedatives.

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11y ago

a barbiturate is an opiate narcotic. prescription painkillers and opiate based narcotics are considered barbiturates. examples: heroin/morphine, prescription narcotic painkillers such as oxycotin, vicodin, perkeset, etc.

barbiturate narcotics are prescribed by doctors mainly for pain managment. they can however be used and sold for illicit drug abuse. this is a narcotic but is not opiate based.this is an anticonvulsant very dangerous.prescribed by a dr.blood test are used to monitor levels in the blood.increased levels can cause death.

Whoever wrote this has no clue as to what they are talking about when it comes to barbiturate. It produces a calming effect, by inhibiting a neurotransmitter in the brain that is normally associated with exciting the CNS central nervous system called GABA. When this excititory neurotransmitter is inhibited by the barbiturates mechanism of action a sedative effect is produced. When prescribed, Barbiturates are not used for treating pain. Barbiturates operate under a completely different pathway than opiate based painkillers. Therapeutic uses are prescribed for anxiolytics, hypnotics, insomnia, and anticonvulsants.

Barbiturates affect the GABA receptors (like GHB) and thereby bring about a general inhibition of the activity of the CNS, especially that part of the brain stem which governs the rhythm of waking and sleeping.

By inhibiting activating stimuli, they induce sleep. The only activating stimuli which are not inhibited by barbiturates are pain stimuli.

Chronic barbiturate users often display irritability and aggressiveness, as well as lethargy, confusion and lack of emotional control (crying). They also display neurological phenomena such as nystagmus, dysarthria and cerebellar ataxia.

As in the case of other CNS inhibitors (like Rohypnol), enforced staying awake after taking barbiturates can produce a paradoxical intoxication, an effect that is also relatively common among the aged and patients with organic disturbances of the CNS.

Barbiturate use leads to an increase in the activity in the liver of the cytochrome P450, leading to a reduction in the breakdown of other exogenous and endogenous substances (including steroids), while stimulating other enzyme systems, so that some drugs have a reduced effect (incl. chlorpromazine, griseofulvin and coumarines).

As a result, disturbances of the endocrine balance regularly occur among chronic barbiturate users and there is a risk of negative interaction with other drugs.

Bibliography:

a1b2c3.com/drugs/barb01.htm

Education Background: B.S. in Biology, Current Med-Student.

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12y ago

Barbiturates are a synthetic drug classified as a

sedative hypnotic. Sedative hypnotics depress

or slow down the body's functions. Often these

drugs are referred to as tranquilizers, sleeping

pills, or simply sedatives. Their effects range

from reducing anxiety to inducing sleep, depending on the amount taken. There are several medical uses for barbiturates,

besides controlling anxiety and sleep

disturbances. They are also used as a mild form

of anesthesia and to control peptic ulcers, high

blood pressure and epileptic seizures.

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8y ago

A barbiturate is a salt or ester of barbituric acid, or any of a variety of derivatives of barbituric acid which act as depressants of the nervous system and are used as sedatives or hypnotics.

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8y ago

A barbituate is another term for a barbiturate, a salt or ester of barbituric acid, or any of a variety of derivatives of barbituric acid which act as depressants of the nervous system and are used as sedatives or hypnotics.

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