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MHC proteins express antigens on a cell surface for T cells to identify whether the antigens presented are self or foreign. There are two classes MHC I and MHC II. They differ in which cells they require to activate depending on the pathogen present.

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13y ago
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13y ago

MHC class 1 molecules are present in all of your cells except red blood cells (they lack nuclei). They bind to antigen and present it on the cells surface to be identified as foreign or self. MHC class 1 is associated with CD 8 T cells (or cytotoxic cells).

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14y ago

CLASS 1 MHC ANTIGENS : are present on all the nucleated cells. they are involved in graft rejection & cell mediated cytolysis.

CLASS 2 MHC ANTIGEN: very limited distribution. found on macrophages,monocytes cd4, b lymphocytes. responsible for graft-versus-host response.

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13y ago

Yes, so every cell in your body except red blood cells.

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13y ago

Genes for MHC will code for chains of MHC class 1 are separate from genes that code for chains of MHC class 2.

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Preksha Amit Patel

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2y ago

rapamycin effects

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Mireille Rempel

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2y ago
thank you

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Q: Difference between MHC class1 and MHC class2 molecules?
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