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What are non-nucleoside reverse transcriptase inhibitors?

In: Biology, HIV and AIDS, Penicillin [Edit categories]

Answer:

delavirdine (Rescriptor), loviride, and nevirapine (Viramune) act by binding directly to the reverse transcriptase molecule, inhibiting its activity.

First answer by Gale Ency. of Medicine. Last edit by Gale Ency. of Medicine. Contributor trust: 37 [recommend contributor ]. Question popularity: 1 [recommend question].

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What is the purpose of non-nucleoside reverse transcriptase inhibitors?
This medication is used to treat patients with the HIV virus and AIDS in combination with one or more other AIDS drugs. Combining NRTIs with older drugs improves their ability to lower the levels of...
Difference between nucleoside reverse trancriptase inhibitor and non nucleoside reverse?
They have a different mode of action in inhibiting the transcription of the viral DNA. The NRTI is actually a nucleoside that incorporates into the viral DNA but it does not have a 3-hydroxyl group...
What side effects do non-nucleoside reverse transcriptase inhibitors have?
A mild skinrash iscommon; a severeskin rashcan be a life threatening reaction. Other possible side effects include fever, blistering skin, mouth sores, aching joints, eye inflammation, headache,...
What precautions should be taken when taking non-nucleoside reverse transcriptase inhibitors?
Patients should not discontinue this drug even if symptoms improve without consultation with a physician.
What adverse effects are possible with nucleoside reverse transcriptase inhibitors?
Lactic acidosis in the absence of hypoxemia and severe liver enlargement with fatty degeneration have been reported with zidovudine and zalcitabine, and are potentially fatal.