Hi There is no easy answer to this because it is a question of personal taste, but there are some ground rules, and the first is your style of music. If you are playing using only clean tones, perhaps for jazz or Mark Knopfler-style pickin, you would probably love the warmth of a pair of 12" speakers with alnico magnets. These are fairly low-powered when compared to a 12" with a regular ceramic magnet, and they will not really handle anything but the lightest bluesy grit, but for jazz they are awesome. Look for the name Jensen, but they must be alnico type, which means Ebay. If you are playing rock you probably want a standard 4x12 slant cabinet and there are more of these than you can shake a stick at, and they can go up in price to over 1000 dollars. When you consider you can buy the speakers in them for less than 100 bucks apiece (the 1000 dollar VHT cabinet is loaded with 4 12" Eminence Texas Heat speakers that you can buy for $75 bucks each!) Websites to look at for information include Marshall or Mesa for mid to upper price range, Behringer or Line 6 have a fairly decent offering at the low price range. The older (and obviously used) Peavey cabinets are also highly regarded. But if you go the Eminence or Celestion websites and look at the descriptions of literally dozens of the actual speakers (not the cabinets they come in) each with a different tone or focus you could spend forever and a small fortune loading a 4x12 with different speakers to find the "right" one. For what it's worth, my son bought a 600 dollar Marshall 4x12 loaded with Celestion G12-75s which he is replacing with the throatier Texas Heats. Your mileage will definitely vary. I suggest if you already own a guitar and amp that you take them to your local music store and try them with as many different boxes as you can. Phil