Yes, it is an interference motor. The valve could contact the pistons if it was out of time.
.2mm for intake and .3mm exhaust. or .008in and .012in when the motor is warm. not sure for cold motor.
Knocking on a Toyota Previa. Try and get someone to read the ECU codes, that will tell you if the problem is from the "Knock Sensor". If it is you will need to buy a new one and replace it. They are...
According to my 1991 owner's manual the gap is 0.031in or 0.8mm for a 22R-E engine.
It weighs around 315 pounds