The question needs some clarification. Each of these are drugs to treat depression. Each can be taken separately. Frequently wellbutrin is added to regimens of Zoloft to try to provide energy or correct sexual problems.
Wellbutrin has a series of potential withdrawal symptoms. It is best to try to taper from a high dose down to a low dose... 300mg, to 150mg, to 100mg to 75mg. Others report that they can stop wellbutrin immediately with no withdrawal. Best to work with your doctor.
Zoloft has a very well documented withdrawal syndrome, with electrical or zappy feelings as one of the events. The original poster of this answer below did not indicate which medication they were withdrawing from or which dosages. The important information is that they recommend a taper down. Zoloft can be tapered very slowly into very small doses. Wellbutrin can be taken in small doses ( a 75 mg can be cut in two). The higher formulations of Wellbutrin can not be cut. Before cutting a pill of anysort both your doctor and a pharmacist should be consulted.
I had major withdrawel symptoms - nausea, vomiting and shakes for 10 days. I HIGHLY recommend "stepping" off these drugs and not stopping cold turkey.
Been on it for 4 months, I went from 450 mg to nothing (hair loss issue) it's been 7 days now, no withdrawal(s) whatsoever it's business as usual, go figure.
Deb