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The most powerful handgun in the world has to be the Austrian Pfeifer-Zeliska .600 nitro express revolver, but the most powerful PRODUCTION handgun is the Smith & Wesson Model 500 revolver that shoots the .500 cartridge.

The .600 Nitro Express Zeliska revolver is an Austrian single-action revolver produced by Pfeifer firearms. It is the largest handgun in the world, weighing in at 6.001 kilograms (13.230 lb) and having a length of 55 centimetres (22 in). The cylinder section alone weighs 2.041 kilograms (4.500 lb). The Zeliska is also the most powerful handgun in the world, producing a muzzle energy of over 6 kilojoules (4,400 ft·lbf). The weight of the gun helps control the recoil, making controlled shooting possible.

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Q: What are the Most powerful handguns?
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