What are the cautions for taking biguanides and thiazolidinediones used for treating insulin resistance?

Answer:
Both classes of drugs have the potential for very severe adverse effects. They are also not approved by the FDA for control of insulin resistance.
First answer by Gale Ency. of Alt Med. Last edit by Gale Ency. of Alt Med. Contributor trust: 16 [recommend contributor recommended]. Question popularity: 1 [recommend question].