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Complications arise in pregnancy when the mother is Rh negative and her partner is Rh positive. If he is Rh negative there will be no complications from Rh incompatibility (hemolytic disease).

While the mother's and baby's blood systems are separate there are times when the blood from the baby can enter into the mother's system. If the baby is Rh positive the mother will react by making antibodies to the Rh factor, when this happens the mother is said to be sensitized. Once the mother is sensitized she will always have antibodies, these antibodies will then attack an Rh positive baby's blood, causing it to break down the red blood cells and anemia will develop. In severe cases the baby may need a blood transfusion at birth to replace the damaged cells.

The best treatment for hemolytic disease is prevention, your doctor will most likely order an injection of Rh immunoglobulin (RhIg), to be given at around 28 weeks.

Once the baby is born a blood test will determine if he is Rh positive or negative. If the baby is Rh negative nothing further is needed, if he is Rh positive you will be given another injection of RhIg to protect any future pregnancies. Each pregnancy and delivery of an Rh positive baby will require repeat doses of RhIg.

You should also receive RhIg following a miscarriage, ectopic pregnancy, or induced abortion to prevent any chance of developing antibodies.

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12y ago
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10y ago

We are looking for the possible blood types of a baby.

Parental information:

  • Mother type B neg = can be BB or BO and only Rh (--)
  • Father type O pos = can only be OO and Rh (++) or (+-)
Baby recieves one gene from each parent:
  • Baby is type BO Rh (+-) = B pos
  • Baby is type BO Rh (--) = B neg
  • Baby is type OO Rh (+-) = O pos
  • Baby is type OO Rh (--) = O neg
NOTE: there is no A gene for either parent.

Generally the baby must be Type B pos/neg or Type O pos/neg

HOWEVER: There is more to ABO blood typing that just the ABO gene.

There is also an inhibitory gene that will change any genotype into the phenotype O.

Therefore a person with genetically AB blood can be tested as having Type O.

  • What if the baby is Type AB neg?
If the father has the inhibitory gene affecting his AA, AO or AB type,

then the Type AB baby is definitely possible.

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14y ago

Yes, there is a chance that if the father is type positive, and the baby is type positive, the mother's antibodies can attack the baby. Make sure your doctor knows and checks on the pregnancy regularly.

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13y ago

It is impossible for a woman with B negative blood to conceive a child with an A negative father.

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Q: What are the chances of complications during pregnancy if mother has B negative blood group?
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