Mainly the feedback (or lack of it) are not the same is in flight and that you know you are in a simulator; no one knows exactly what they will do when in an actual emergency.
1) the invaluable flight hours without the cost of fuel and flight maintenance
2) simulation of life threatening situations (no power landings, stuck gear) without the actual loss of life
3)...
Trains are not always the fastest way to travel. Some trains only run once every few days and may not stop where you want to go. Subways can be noisy, cramped, drunks can cause hassel, stangers...
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