The Ohio State Buckeyes and The Michigan Wolverines.
The 1971 Nebraska-Oklahoma game. Nebraska was the defending national champions and was ranked #1. Oklahoma was ranked #2. Nebraska had the #1 defense in the country and Oklahoma the #1 offense....
Maryland vs. Clemson
Ohio State and Michigan UniversityCorrection, Ohio State and the University of Michigan. In which, Michigan leads the series 57-42
Harvard vs. Yale- started in 1875