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In Diabetes mellitus, glucose can't enter the body's cells from the blood, since insulin is low (or ignored). Blood glucose begins to rise. When blood glucose gets high enough, it passes the 'renal threshold' for sugar. (In humans this is between 180 and 220 mg/dL.) The kidneys are then obliged to filter out glucose and excrete it with the urine.

At this point, the urine becomes too concentrated and osmosis pulls extra water into the urine from the body, leading to the polyuria symptom. The resulting dehydration makes the victim thirsty -- this is the polydipsia system.

The sugar being wasted by the kidneys means the body is not nourished, even with enough food intake. This leads to excess hunger or polyphagia.

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Q: What are the physiologic mechanisms involved in polydipsia polyuria and polyphagia in diabetes mellitus?
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Related questions

What are the cardinal signs of diabetes mellitus the 3 p's?

Polydipsia, polyuria, and polyphagia(also called the three poly's) areclassic symptoms typically associatedwith Type 1 diabetes, others includeunexplained weight loss, irritability,poor wound healing, dizziness andblurred visionPolydipsia, polyuria, and polyphagia


Polyuria polyphagia polydipsia and weight loss are all sign of what?

Diabetes mellitus


What are the 3 Poly's in diabetes?

Polyuria (frequent urination)Polydipsia (increased thirst)Polyphagia (excessive eating)


What conditions result in Polyuria and Polydipsia?

Diabetes


What are the four polys- for diabetes mellitis?

I don't think that there are four (4) polys.....However the three (3) that I know of are: Polyurea....Polyphagia....& Polydipsia! Poly = Many urea = urination phagia = eating dipsia = drinking. Poly (many) urea (urination)


Blood tests for diabetes?

Diagnosis of diabetes can be made with an oral glucose challenge (if the diagnosis is uncertain), by a fasting blood glucose of > 125mg/dL, or a random blood glucose of > 200mg/dL, when accompanied by any symptoms concerning for diabetes (polydipsia, polyuria, polyphagia, or weight loss). The glycosylated hemoglobin (also called HgbA1c) will also be elevated, but this is not currenlty used to diagnose diabetes.


What ways you can detect diabetes?

Patient may come with a classic triad of polydipsia, polyphagia and polyuria. That drinking extra water, eating extra food and urinating a lot. He may come with diabetic coma. You detect diabetes by doing the blood glucose level.


What symptons do you have in diabetes?

The symptoms of diabetes are mainly polyphagia or increased hunger, polydipsia or increased thirst, polyuria or increased frequency of urination and manifestations of polyneuropathy like tingling and numbness, muscle weakness in any of the limbs. There can also be non-healing wounds as a manifestation of diabetes.


What is the term meaning excessive thirst?

Polydipsia is the term for excessive thirst. It can be a symptom of Diabetes mellitus or diabetes insipidus.Polydipsia


Is dehyderation and polydipsia a degenterative illness?

Dehydration and polydipsia are not illness in themselves. They are signs and symptoms of conditions that may be an illness or disease. They are both common in someone that has diabetes.


Give the symptoms for diabetes Mellitus?

The most common symptom is the diabetes triad. The 3 P's namely Polyuria or excessive urination, Polydypsia or excessive thirst and Polyphagia or excessive hunger.


What are the cardinal symptoms of diabetes meelitus and provide the rationale for the occurrence of each symptom?

polyuria- high sugar content in kidneys filtrate causes large amounts of water to be lost in urine Polydipsia- thirst due to large volumes excreted Polyphagia- hunger because blood sugar cannot be used as a body fuel even though blood levels are too high