ZOLOFT ( sertraline ) for depression and OCD (obsessive-compulsive disorder) and STRATTERA, for ADD/ADHD and lack of concentration, don't seem to have any noted problem when taken together. For a COMPLETE LIST of side-effects for both medications, please see your PHARMACIST and ask for a print-out on both meds. ANY pharmacy should glady honor your request, even if you did't fill your prescriptions there. They are very knowledgeable and helpful. Best Of Luck!