What are the step in the blood clotting process?

Answer 1

The 3 stages of hemostasis are:

1) Vascular Spasm where there is a high resistance to blood flow as arterioles leading to the damaged area vasoconstrict.

2) Platelet Plug: is wher sticky cell fragments adhere to the site of the damaged blood vessel and the aggregated platelets secrete Adenosine Diphosphate causing more platelets to aggretage and congrugate around the blood vessel

3) Blood Clots: blood clots become trapped in fibrin mesh....fibrin comes from fibrinogen and goes through a process to form fibrin called coagulation cascade. The fibrin adhere to one another forming a mesh. The mesh becomes stronger by Factor VIII stabalizing the bond on the fibrin.

Answer 2

Blood clotting occurs in 5 steps:

1. Broken down blood vessels attract platelets to the site

2. As platelets collect they release chemicals that react with plasma to produce the enzyme thromboplastin

3. In the presence of calcium ions, thromboplastin reacts with prothrombin to produce thrombin (another enzyme)

4. Thrombin reacts with fibrinogen to produce fibrin 5.

Fibrin is an insoluble material that forms a mesh of strands around the area of injury

Answer 3

When you cut yourself you bleed. Before long, platelets help the blood to thicken and the bleeding stops. The thickened blood has formed a clot. without clotting, blood would be lost and pathogens would enter.

Answer 4

1. immediately after injury vascular constriction occurs at injury site which limits the flow of blood to the area of injury. Coagulation of the blood is initiated by the blood platelets. 2. The platelets produce a substance that combines with calcium ions in the blood to form thromboplastin, which converts the protein prothrombin into thrombin which forms a temporary platelet plug at injury site. The thrombin converts fibrinogen into fibrin, fibrinogen is primarily responsible for stimulating platelet clumping. 3. Fibrin, an insoluble protein then forms an intricate network of threadlike structures called fibrils and causes the blood plasma to gel. 4.The blood cells and plasma are enmeshed in the network of fibrils to form the clot

Answer 5

These are the three phases:

Phase 1: Formation of prothrombin activator

The prothrombin activator is formed through intrinsic and/or extrinsic pathway. Usually it is formed by both. Its formation is triggered by tissue-damaging events and it involves a series of procoagulants. Each pathway cascades towards Factor X (i.e. the Stuart Factor) that complexes with Ca2+, platelet factor 3 (PF3), and Factor V to form the prothrombin activator.

The intrinsic pathway is triggered by negatively charged surfaces of activated platelets, collagen, and glass and it uses factors present within the blood. As for the extrinsic pathway, it is triggered by exposure to tissue factor (Factor III). The extrinsic pathway bypasses several steps of the intrinsic pathway so it is faster. Once the prothrombin activator is formed, the clot forms in 10-15 seconds.

Phase 2: Prothrombin's conversion to thrombin

The prothrombin activator catalyses the transformation of prothrombin to thrombin.

Phase 3: Fibrinogen conversion to fibrin

Thrombin (Factor II) converts soluble fibrinogen to the solid fibrin. The fibrin formed will cause the plasma to become a gel-like trap for formed elements, forming the structural basis of the clot. The thrombin along with Ca2+ activates Factor XIII to cross-link fibrin. This will strengthen and stabilise the clot.

Answer 6

Describe the three phases of the normal blood-clotting process.

Answer 7

Prothrombin-->Thrombin; Fibrinogen--> Fibrin (activated by thrombin)
The sequence of blood clotting is called Coagulation.

Answer 8

1 blood 2starts 3to 4clot