The play 'Antigone' still is read over 2,440 years after its writing because of the universality of its themes to all cultures, throughout all places and times. For example, a major theme is the permissible reaction to perceived inhumane, unfair, unjust, unpopular laws. For example, Antigone decides not to obey the law of her uncle, Theban King Creon, because it contradicts the perceived god-given traditions by which Thebans live their lives and prepare for their deaths.
Another major theme is the reconciliation of personal beliefs with the legal demands of society. Antigone doesn't make that compromise. For she believes in god-given rights to a proper burial, be the Theban in good or bad standing before the ruler and the rules.
Still another major theme is the role that gender gives the individual in society. For example, Ismene believes that being female denies one the right to make life-altering choices. She sees men as stronger, women as weaker. The difference entitles men to rule, and women to obey.