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The symptoms people get from MSG consumption are not due to an allergy. The active componet of MSG is glutamic acid which is used as an excitatory neurotransmitter in the brain and is used in many other parts of the body as well. And it's the overstimulation of these nerve cells, including brain cells, by the excess glutamic acid that cause most of the symptoms.

Some people are extremely sensitive to MSG, such as myself, and therefore can have more problems with MSG than other people. There are many causes for this increased sensitivity, such as nutritional deficiencies, excess calcium intake, and a damaged or immature blood brain barrier.

Some supplements that can reduce sensitivity to MSG:

Theanine

Taurine

Magnesium (Magnesium Gluconate on empty stomach)

Zantac may also help as it's an h2 antihistamine which can reduce blood brain barrier permeability and therefore reduce the amount of MSG(glutamic acid) that enters the brain.

Another possibility is that many MSGish ingredients contain higher histamine from production and cause symptoms in people with histamine intolerance and in that case a supplement called Histame may help. It contains a natural enzyme that breaks down histamine in foods.

While I have listed some supplements that provide some protection against excitotoxicity, I recommend trying to avoid products that contain MSG as well. Excess glutamate in the brain, including that from MSG, can cause cumulative brain damage.

MSG has become unpopular and so in many cases other ingredients, which contain free glutamic acid, are used in place of MSG. A few examples include hydrolyzed proteins and natural flavors, but there are many more.

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11y ago
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14y ago

People can be allergic to almost ANYTHING. Which includes MSG. MSG is a salt substitute that fast food chains use because it's cheaper and it actually makes the food your eating taste better. The answer to the question is, YES. You can be allergic to MSG.

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It's actually not an allergy to MSG. The active part of MSG, glutamate, is used as a neruotransmitter in the brain and other nerve cells. Excess glutamate can overstimulate these brain cells and other nerve cells throughout the body and cause many different symptoms. Some people are very sensitive to MSG, but they're not allergic to it. One study showed that 25% of the people who consumed MSG in a meal reported having symptoms following MSG consumption. But when the people where given MSG without a meal in the morning, after being in a fasted state all night, all of the people reported symptoms from the MSG. Even moderately low blood sugar such as being in a fasted state all night or intense exercise will make you more sensitive to MSG.


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