The drugs are classified as pregnancy category C, based on evidence of inhibition of fetal growth in rats given more than four times the normal human dose.
The sulfonylureas are classified as category C during pregnancy, based on animal studies, although glyburide has not shown any harm to the fetus and is classified as category B.
Currently, no antidepressant medications are classified in pregnancy category B. Wellbutrin (bupropion) is the only antidepressant that was classified by the FDA in pregnancy category B, in the past....