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What causes abnormal shapes to red blood cells?

In: Genetics, Blood [Edit categories]

Answer:

Sickle-cell disease is a genetic disease that results in abnormal hemoglobin molecules. When these release their oxygen load in the tissues, they become insoluble, leading to mis-shaped red blood cells. These sickle shaped red cells are rigid and cause blood vessel blockage, pain, strokes, and other tissue damage.

First answer by MIGUEL VERM. Last edit by MIGUEL VERM. Contributor trust: 24 Question popularity: 2 [recommend question].

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What causes the shape of a red blood cell?
Spectrin
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You can see pictures by following the related links below. A general description though: a mint with a slightly indented middle on both sides.... That's so that it can carry oxygen to the cells...
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