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a slightly low serum globulin probably has no significance, say 1.9 (where the low end of normal range is 2.2 or 2.3) unless associated with some other disease, such as kidney nephrosis or liver disease.

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13y ago
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9y ago

The globulin is calculated by albumin minus total protein . A low A/G level reflects an overproduction of globulins and may indicate chronic infections.

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12y ago

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Q: What causes globulin to be low?
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Related questions

What does it mean if you have low globulin in a blood test?

low immunity


What causes globulin to get high?

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What does globulin 2.0 albumin globulin ratio 2.4 mean?

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If Albumin is 4.0 Globulin is 4.1 and Ag ratio is 1.0 what could that mean according to chart albumin is in range globulin is high and ag is low?

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Which substance is is most likely to pass from blood capillary to lymph capillary A alpha globulin B beta globulin C fibronogin D IgM E albumin?

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What may cause a Combination of low calcium and low total protein and low globulin on a blood test?

Low globulin can be due to immune deficiency associated with decreased antibody production. This would also account for lower total protein (because globulin is a protein), however it would not account for the low calcium level. Calcium is bound to protein in the blood, so low protein can be associated with a spruriously low calcium (i.e. a calcium number that is low without actual calcium deficiency). This may be the case if the albumin (another protein) is low, and there is a formula to correct calcium for low albumin, where: Corrected Calcium = (0.8 * (Normal Albumin - Pt's Albumin)) + Serum Ca Alternatively, an ionized calcium level can be checked and will be normal if the serum calcium was only low due to low albumin. Without knowing the clinical context (which would be very helpful), the most likely single explanation for low globulin, low total protein, and low serum calcium is protein nutritional deficiency. In this case, the body is overall protein deficient and so it is not uncommon to find a decrease in all protein levels (especially if severe). In this case, the low serum calcium is due to low albumin, as above. This can be further explored by checking a pre-albumin level (typically low if protein deficiency due to poor diet). You should talk to the physician who orderd the tests for a better answer, as only he or she knows why the tests were ordered and can interpret them in the appropriate clinical context.


What is Varicella zoster immune globulin?

Varicella-zoster immune globulin (VZIG)-- A substance that can reduce the severity of chickenpox symptoms.


What is the cost of IVIG globulin?

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How are immunizations and immune globulin different?

immunization is the antibody giving to the human to get the immunity. but immun globulin is existing antibody in the human body.