Port-wine stains are present at birth, and seizures may occur in early childhood. If an individual has both of these features, SWS should be suspected.
The prognosis for people with SWS is directly related to the amount of brain involvement for the leptomeningeal angiomas. For those individuals with smaller angiomas, prognosis is relatively good.
Individuals with the Pickwickian syndrome are overweight, with large necks, fat buildup around the soft tissues of the neck, and loss of muscle tone with aging.
Cauda equine syndrome is a serious condition that may cause loss of all nerve function below the area of compression, which can cause loss of bladder and bowel control.