Yes, it is the second largest city in the state.
Columbia, the place in Richland County, South Carolina, USA
Columbia.
That would also be the Capital city, Columbia. 2000 population has it listed at 116,278 while 2008 estimates have it just over 127,000.
The first one is Charleston but back the known as CharlesTowne, The secound is Beaufort South Carolina which is home to most historic sites and the third is GeorgeTowne named after King George 1