The pancreas produces insulin and digestive enzymes. Therefore removal of the pancreas will require the patient to take insulin to regulate blood sugar.
Also, the digestive enzymes the pancreas used to make will now be a pancreatic enzyme supplement taken with food. If this supplement is not taken the patient may fail to properly absorb foods resulting in loose stools and weight loss.
Close monitoring of blood sugar, along with follow-up by an endocrinologist can help improve the long-term outcome of patients.