What do you feel is the best handgun caliber for general self defense?

Answer:
No one answer possible. It will be a caliber with the best stopping power that you can shoot well, and is 100.00000% reliable. For some people, that is a .327 magnum, for some, a .45 ACP. I personally carry either a .357 Magnum or a compact .45 ACP, but both have too much recoil for my wife- who does very well with a .38 Special. As is often said- Your Mileage May Vary. Would suggest you visit a range that rents handguns for use on that range, and try as many as you can to see what works for you. A 250 lb football player and a 95 lb woman may have different needs and abilities- you did not say which one you were.
First answer by C3shooter. Last edit by C3shooter. Contributor trust: 352 [recommend contributor recommended]. Question popularity: 0 [recommend question].