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Vitamin K is considered an "antidote" for warfarin overdose.

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Q: What do you give a patient for a warfarin overdose?
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Is it dangerous to have a 6.5 blood level of Coumadin or Warfarin sodium which is above the level 2 that is recommended and what should be done?

I am assuming by "blood level" that you mean the International Normalized Ratio (INR), as we do not normally check the actual blood level of Warfarin. Warfarin is a commonly used anticoagulant (blood thinner) medication. The level of INR that a patient requires actually varies depending upon the condition they are being treated for. 6.5 is never a therapeutic goal for Warfarin. Elevated INR levels indicate that a patient may bleed. The management for an INR of 6.5 depends upon the presence of bleeding. If the patient is not actively bleeding, it is appropriate to hold the next two scheduled doses of Warfain and monitor the INR. The Warfarin may be resumed when the INR is back to range. IF the patient is bleeding, the Warfarin will need to be stopped and Vitamin K needs to be administered, as well as medical treatment for bleeding. This would be the standard of care in this case.


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