To patronize is to look down on some one. So for example u were at a salon and a hair dresser looks at you and says "oh let me fix your hair, i can make it look better" than you would say "don't...
"It means just what it sounds like - something doesn't mean anything. It is not a grammatically correct idiom, which is why it probably sounds odd. The original usage was from a song "Don't mean a...