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About 1487.
Not a painting, but a drawing, called Vitruvian Man.
Vitruvian Man was made as a study of the proportions of the male human body as described in a treatise written by ancient Roman architect, Vitruvius.
34.4 x 25.5
so it can help in measurements.
Assuming you mean his "Vitruvian man" (the one standing in the circle with his arms stretched out) that was made around 1487.
There is a scene in the begining of The Da Vinci Code where the murder victim is arranged as the Vitruvian Man.
The Vitruvian Man - 2005 was released on: USA: 11 March 2005 (New York International Independent Film and Video Festival)
The Vitruvian Man was drawn by Leonardo da Vinci. It is a famous drawing that illustrates the ideal proportions of the human body as described by the Roman architect Vitruvius.
About 150 million dollars
Vitruvius was an turn of the millenium architect who held the belief that the perfect human dimensions where-out stretched arms finger tip to tip will be the same as head to toe and the navel.dead center. Vitruvius was a likely influence on da vinci.
Accademia di Belle Arti in Venice, Italy.