Gran is short for granulocyte. The White Blood Count (WBC) in a blood test result is broken down into Granulocytes (GRAN) and Lymphocytes (LYM). White blood cells are part of the immune system. An elevated level of granulocytes is indicative of a bacterial infection.
Granulocytes are less specific in the type of cells they attack so they can cover a broader range of infection. They are involved in the breakdown of tumor cells while promoting the repair of damaged tissue. They are also involved in the release of histamine which causes the release of prostoglandins which is responsible for the inflammatory process which occurs in the presence of infection by bringing more blood to the area as well as preventing microbes from leaving the area before they can be destroyed & thus are responsible for the prevention of infection by way of a physical barrier.
A low level of granulocytes should be followed-up with additional testing to determine the reason. The immune system is highly dependent on many different things working together. The white blood cells are made by bone marrow & a low level in and of itself doesn't point to anything specific however, it is very important to have a follow-up visit to your doctor along with additional blood work in order to determine the cause. As with many of the maladies to which the human body is subject the vast majority have a better prognosis when detected early.
God Bless,
Maegi
Decreased lymphocytes can show immune system disorders-lupus, HIV. Increased granulocytes are often a sign of bacterial infection or inflammation. Severely increased granulocytes could mean a bone marrow disorder.
Granulocytes are formed in red bone marrow, or myeloid tissue.
Granulocytopenia is the medical term meaning deficiency of granulocytes.
The Philadelphia chromosome can be seen in the granulocytes.
Granucytes are a type white blood cells which has granules in it cytoplasm. They are also called polymorphonuclear leukocytes. there are 3 types of granucytes these are: Neutrophil granulocytes Eosinophil granulocytes Basophil granulocytes
neutrophils
Macrophages.
The normal range for granulocyte percentage is 45.5 - 79.7%, which translates into a normal granulocyte count of 2.2 - 8.8 x 10^3/uL. Granulocytopenia is an abnormally low concentration of granulocytes in the blood. This condition reduces the body's resistance to many infections. Closely-related terms include agranulocytosis (no granulocytes at all) and neutropenia (deficiency of neutrophil granulocytes). Transfusion of granulocytes would have been a solution to the problem. However, granulocytes live only ~10 hours in the circulation (for days in spleen or other tissue), which gives a very short-lasting effect. In addition, there are many complications of such a procedure. If you have a high percentage be happy!!!cheers
Granulocytes can be identified when their cytoplasmic granules are stained with Wright's stain. Agranulocytes do not have cytoplasmic granules so they will not have stained granules.
in red bone marrow
neutrophils, eosinophils, and basophils
Red bone marrow