Elevated Immunoglobulin levels typically indicate an current infection in the body. What kind of infection is determined by the type of immunoglobulins that are elevated. Immunoglobulins are membrane bound to naive B cell. An antibody is a secreted form of immunoglobulin that is used to fight infection directly or indirectly in various ways. Elevated immunoglobulin levels could also be a result of some lymphomas, especially if one particular immunoglobulin is extremely elevated over the others due to clonal expansion of the mylomal tumor.
Immunoglobulin E (IgE)
There are five immunoglobulin classes (isotypes) of antibody molecules found in serum: IgG, IgM, IgA, IgE, and IgD. IgA (immunoglobulin A) IgD (immunoglobulin D) IgE (immunoglobulin E) IgG (immunoglobulin G) IgM (immunoglobulin M)
The relationship between IgE antibodies or immunoglobulin E and thyroid is that an increased level of these antibodies can lead to Grave's disease. It is believed that the immunoglobulin antibodies actually lead to this thyroid disorder.
Immunoglobulin E (IGE) mediates many acute allergy reactions, including anaphylaxis. Immunoglobulin G (IGG) mediates more delayed sensitivity reactions, slower onset and over prolonged period.
Skin prick tests are measured in millimeters (mm). Blood test check levels of Immunoglobulin E.
High IgG levels does not lead to a diagnosis without further details of the types of IgG which are elevated. An increase in certain IgG subclasses is associated with diseased states especialy IgG4 in allergic diseases, asthma and cystic fibrosis. With the wording used in the question it could imply that the person is mearly at the outlying area of normal distribution (reference range), just as some people are "tall" some people have naturally high IgG titers. On the plus side a high IgG titer means it is highly unlikely (but not impossible) that the patient has any immunodeficient diseases associated with IgG.
The genotype cDEcde indicate that D & E are dominant genes.
Marian E. Beratan has written: 'Intravenous immunoglobulin' -- subject(s): Immunoglobulins, Bibliography 'Wrongful life' -- subject(s): Bibliography, Pregnancy, Unwanted, Unwanted Pregnancy
IgE, also known as immunoglobulin E serum is a test to measure the level if IgE in the blood. IgE is a class of antibodies made by the immune system.
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