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ANA means anti-nuclear antibodies. There are antibodies that a person might make against the nuclear material of their own cells that have died, broken down and are circulating in the blood stream. 10 million Americans have a positive ANA. Many have no disease. The older one is, the more likely one is to have a positive ANA.

The ANA test is a titer which means the number represents how many times the lab had to dilute the blood to come up with a sample with no autoantibodies.

IFA refers to immunofluorescence. People with lupus who have a positive ANA are likely to have a speckled pattern under immunofluorescence.

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Q: What does ana screen ifa positive?
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If you have lupus, you will almost definitely have a positive ANA. However, a positive ANA doesn't necessarily mean you have lupus.


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Hashimoto's thyroiditis is an autoimmne disease that affects the thyroid gland. A positive ANA means that a person makes anti nuclear antibodies. The person makes antibodies against the debris from the natural breakdown of the nucleus of dead cells. 10 million Americans have a positive ANA, many have no disease at all. The older you are, the more likely you will have a positive ANA. In disease, what matters more than just testing positive is the immunfluorescent pattern, with each pattern indicating a different autoimmune disease.


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