Mean platelet volume is the size of the platelets. The higher the MPV the larger the platelet size and the lower the MPV the smaller the platelets. High MPV can cause a person to be at a higher risk for strokes and heart attacks. Low MPV can cause a person to be at risk for bleeding problems (too much bleeding that is slow to stop). There are some natural anti coagulants that help lower MPV blood like flax seed oil and fish oil.
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A high lymphocyte and platelet count could indicate that you are suffering from some sort of infection, as viruses will cause these numbers to be higher. More serious problems that can be indicated by high counts are cancer and diseases of the bone marrow.
my platelet count is 681, with neuts at 19.6, white blood cell count over 26, and Vitamin B12 count at 917 - all way above the average range. What does this indicate?
Thrombocytosis, including essential thrombocytosis is seen in high counts. You may clot easily and you may have to take a "clot buster" like Warfin.